Nima Gharahdaghi
Nima is a postdoctoral research fellow in translational immunology at the University of Oxford, where his work focuses on understanding the biological heterogeneity of immune-mediated inflammatory diseases and how this can be translated into more personalised approaches to diagnosis and treatment.
His research particularly investigates cytokine signalling, autoantibodies and immune dysregulation in inflammatory bowel disease (IBD). His recent work has examined neutralising autoantibodies against IL-10 and their potential to identify a biologically distinct subgroup of patients with IBD. More broadly, he is interested in integrating functional immunology with biomarkers and patient stratification to understand why apparently similar patients can have different disease mechanisms, trajectories and responses to therapy.
Through his work with the Centre for Personalised Medicine, Nima is particularly interested in communicating emerging developments in precision immunology to wider scientific, clinical and public audiences, and in exploring how mechanistic discoveries can be translated responsibly into clinically useful personalised medicine.