The Oxford Personalised Medicine Society was thrilled to host Professor Sir Mark Caulfield, Chief Scientist for Genomics England and charged with delivery of the 100,000 Genomes Project. Professor Sir Caulfield is additionally director of the NIHR Biomedical Research Centre at Barts and the London school of Medicine and Dentistry. He was Director of William Harvey Research Institute (2002-2020), elected to the Academy of Medical Sciences in 2008 and was President of the British Hypertension Society from 2009-2011.