Hosted by: Oncologists United for Climate and Health (OUCH) and the Centre for Personalised Medicine, University of Oxford Climate change is the biggest threat to health globally. Extreme weather events, food and water shortages, infrastructural challenges and forced migration, will change the patterns of disease we see and disrupt the provision of cancer care in all countries. These challenges will have the greatest impact on more vulnerable populations, who have contributed the least to man-made climate change. In addressing these impacts, we must also acknowledge that cancer care itself has a significant carbon footprint and environmental impact, and work to reduce these. In this first London Global Cancer Week session on Cancer and Climate, we will discuss some of the key challenges for the global oncology community, and consider how these may be addressed, ahead of COP28.